Allele-specific gene expression in a wild nonhuman primate population

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Allele-specific gene expression in a wild nonhuman primate population.

Natural populations hold enormous potential for evolutionary genetic studies, especially when phenotypic, genetic and environmental data are all available on the same individuals. However, untangling the genotype-phenotype relationship in natural populations remains a major challenge. Here, we describe results of an investigation of one class of phenotype, allele-specific gene expression (ASGE)...

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Genetic variation in populations can result in variation in levels of gene expression but the extent to which this occurs has been unclear. In this article, recent studies of allele-specific expression among autosomal non-imprinted genes are reviewed. These new data provide evidence that differential expression is relatively common and that allelic differences are heritable and can be highly co...

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ژورنال

عنوان ژورنال: Molecular Ecology

سال: 2011

ISSN: 0962-1083

DOI: 10.1111/j.1365-294x.2010.04970.x